Posts tagged with "cancer"

image from Dina Allende for use by 360 Magazine

AUTOMOTIVE GROUP FIGHTS AGAINST BREAST CANCER

Two Automotive Executives Become Co-Chairs of the 2021 Making Strides Against Breast Cancer® Event in Broward

For the Craig Zinn Automotive Group, joining the fight against breast cancer hits close to home. That’s why two top executives from that organization have stepped up to co-chair this year’s Making Strides Against Breast Cancer Broward presented by Seminole Hard Rock Hotel and Casino – Hollywood, scheduled for October 23, 2021. Fleet manager for Lexus of Pembroke Pines, Michele Alter, is a 21-year breast cancer survivor, and Brittany Zinn, assistant group general manager/CZAG, lost a maternal figure to breast cancer. The two plan to work closely with Trudy Spence, senior development manager at the American Cancer Society® Fort Lauderdale to make this year’s event a success.

The American Cancer Society Making Strides Against Breast Cancer® (MSABC) is a national movement. Fundraising events range from large-scale traditional walks to unique local experiences and celebrations. Making Strides has united communities, companies and individuals across the country in the fight to end breast cancer for more than two decades. The organization has known of Michele and her fight since 2002, when she first started participating in their events. Both Michele Alter and Brittany Zinn believe in MSABC’s commitment to create a future that’s free from breast cancer. “As we look to the road ahead, we are more determined and more inspired than ever before. It will unite Broward County communities to honor cancer survivors and caregivers touched by the disease and raise awareness and funds for a world without breast cancer,” said Trudy Spence. In years past, this event has raised over 700,000 dollars, which went towards funding breast cancer research and programs geared towards both men and women. At this time, the event will move forward in person, but it will keep federal, state, and local health guidelines in mind. As the fall season approaches, event-based decisions may be made to best meet the health and safety needs of everyone involved. Michele and Brittany hope to get as many people signed up to help raise funds. “Between now through October, people can fuel the fight against breast cancer by fundraising. It’s as easy as downloading the American Cancer Society FUNdraising App, which will allow you to register for the October event and ask for donations via email, text and social media,” said Michele Alter who was first diagnosed with breast cancer at the young age of 32.

For many, being diagnosed is a life changing experience, and Michele believes that cancer lit a fire in her soul. Early during her treatment, she decided that she would not only beat cancer, but she would also volunteer and help The American Cancer Society fund a cure. “They were there for me when I needed them the most, so I feel blessed that I am here today ready and able to co-chair this year’s Making Strides/ Broward event.” Michele believes in the programs, because they were the only thing that helped her see the light during those moments of darkness. Brittany comes from an automotive family that happens to also be highly philanthropic. Her father, Craig Zinn, encourages everyone in his company to give back to the community. Despite wearing many hats, Brittany was eager to serve as co-chair for this year’s event to honor the memory of Ingrid, who was like a mother to her. “I’ve seen what breast cancer does to a person. Since I was young, Ingrid kept the true depth of her struggles from me. Had I known, I would have been there for her, much like The American Cancer Society was for Michele,” said Brittany.

According to the American Cancer Society journal, a Cancer Journal for Clinicians, there will be an estimated 1.9 million new cancer cases diagnosed in 2021 and 608,570 cancer deaths in the United States. Given the pandemic, it’s believed that people with active cancer may be more susceptible to COVID-19, because of their impaired immune system. For that, the Broward chapter wants to ensure everyone that even if they cannot attend in person, the success of this event will depend on enthusiastic individuals who commit to raising funds, in addition to generous donors who will support those participants.

WHEN:

Saturday, October 23, 2021, at 8:00 a.m.

WHERE:

Huizenga Plaza, 32 E Las Olas Blvd, Fort Lauderdale, FL 33316

REGISTRATION:

Click HERE to join the walk by signing up as an individual or team. Be sure to download the app to your phone and link the dashboard to Facebook. Fun Fact: Those that connect their fundraiser to FB, raise seven times more money.

image from Dina Allende for use by 360 Magazine

Participants at the 2019 event

Kaelen Felix illustrates Twin Towers for 360 Magazine

How Has 9/11 Changed America?

September 11, 2001 will forever remain etched in the memories of Americans. Almost 3,000 innocent lives were lost during the deadly 9/11 terror attack. No one saw it coming until two planes hijacked by terrorists crashed into New York’s World Trade Center.

Terrorists aboard a third plane hovered around the Pentagon while the fourth crashed in Pennsylvania. And this was the beginning of significant changes in America’s history. Nearly everything changed in a bid to make America safe. Below are several things that changed after the terrorist attack.

Start Of War On Terror

The 9/11 terrorist attack on U.S. soil marked the beginning of America’s war on terror. Before then, American troops were home. But a month after the attack, American troops were deployed to Afghanistan. Their main objective was reining in al-Qaeda militia – an outlawed terror group – behind the terrorist attack in the U.S.

In an address to Congress nine days after the attack, declared a global war on terror.

“Our war on terror begins with al Qaeda, but it does not end there. It will not end until every terrorist group of global reach has been found, stopped, and defeated,” Bush’s resolute stand read.

The U.S. troops sustained a long war in dismantling the Taliban government supporting al-Qaeda. It is the most protracted military campaign in the annals of U.S. history. And it didn’t end here. Military troops from the U.S. in 2003 invaded Iraq intending to dethrone Saddam Hussein. Hussein was the leader at the time and was producing weapons for the Taliban forces.

Twenty years later, about 8,000 US troops are still in Afghanistan, taming the Taliban insurgency.

Health Complications

Residents of lower Manhattan in New York reported increasing cases of Ground Zero respiratory diseases five months after the terror attack. Some of the 9/11 related illnesses came as a result of pulverization. When the World Trade Center collapsed, all materials in the building became fine dust spreading all over Manhattan.

The World Trade Center Health Program certifies that there are more cases of respiratory diseases since the attack in the area. Further, other ailments certified by the program include asthma, anxiety, post-traumatic stress disorder, cancer, depression, rhinosinusitis, and sleep apnea.

Onset Of Deportations

The Department of Homeland Security didn’t exist before September 11, 2001. President Bush formed it in 2002, working closely with the U.S. Immigration and Customs Enforcement (ICE). Deportations rose exponentially during Barack Obama’s administration, having the highest numbers. Between 2009 and 2010, nearly 400,000 people were deported.

Between 1999 and 2001, there were at least 200,000 annual deportations. But they doubled after the 9/11 terror attack.

Airport Security More Elaborate

In 2001, you would wander around the airport in the U.S. without much fuss. Today, you need a ticket to do this. And proper scrutiny of your passenger I.D. is undertaken before boarding a flight. A thorough body check happens today, and you must remove your shoes and your belt. Back then, none of this happened. Security is now elaborate – nothing is ignored. Not even the vaguest intelligence report.

Anti-Muslim Bias

Between 2015 and 2016, FBI data indicates 91 cases of assault stemming from anti-Muslim bias. In contrast to 2001, after the 9/11 attack, this number grew. Americans perceive Islam as a religion advocating for war. Religious discrimination is still a thing in America. The profiling of Muslims continues amid efforts to change the narrative that they are peace-loving.

The aftermath of the 9/11 terror attack in the U.S. in 2001 has a good and an ugly side. In terms of safety, it is a plus for the people. More elaborate security systems are in place today. But America is still in the war two decades later; this is a sad reminder of the aftereffect of the most significant terror attack in the land.

health via 360 Magazine for use by 360 Magazine

Brain Tumor Infocon

By: Skyler Johnson

The Brain Tumor Infocon was an event that took place this past week, via Zoom because of the pandemic. The event was not for cancer patients themselves but for those that cared for them. They gave four talks on four separate days, each regarding a different topic. I attended the workshop focusing on children and young adults. All different types of people attended, from parents caring for children to friends caring for friends. But they came for the same reason, to try and gain advice towards dealing with cancer patients. And hopefully they left gaining more information then they had entered with. Here’s what I learned from the event:

Brain Cancer Changes Who a Person is

This must be terrifying to go through, but it does make sense. After all, the brain is where a person’s thoughts, feelings, and emotions are stored, and cancer destroys that. When a person has cancer you have to see them change. There’s not much anyone can do about it, there’s no way to prevent it, but it is something that happens nonetheless. 

Don’t Be Afraid to Say “Cancer”

For a person with cancer, it can be incredibly isolating when their caregiver doesn’t use the actual word. For children, it can be hard to understand what’s wrong with them if they don’t know what they’re going through if they don’t have the actual term to define it. It’s the same with emotions. Caregivers shouldn’t be afraid to show emotions just because they don’t want to upset those they’re caring for. It’s another thing that can make people feel very alone. 

The Question Jar

The presenter recommended a question jar for child patients who may be shy about asking questions regarding their cancer. The caregiver, a parent, would leave the jar in a heavily trafficked part of the house, like a kitchen or living room, and the child can put questions in the jar whenever they’d like. The caregiver would answer their questions periodically, not directly after the child put the concern in. You wouldn’t want them to know you’re keeping track. 

Feel Free to Take Time for Yourself

Having to take care of a cancer patient can be a daunting task, and one thing that was heavily encouraged was having caregivers taking time for themselves. They can’t be there for another person if they can’t be there for themselves. Exercise. Watch TV. Walk the dog. Anything that’ll help calm.

Everyone has a Different Definition of Caring

This is the first lesson I learned, and the most important. The presenter asked the group how they defined caring, which is not something I’d thought about previously. Several of the attendees answered, each in different ways. To some people, caring meant what caring means to most people: helping someone else through their day, making sure they’re content. If I answered the question I might’ve used an anecdote. But for one person it meant “loving and hurting,” which is, I can imagine, the most accurate. Caring can be painful. Caring can be suffering. Because you have to watch them fall apart, and get emotional in front of them, and despite all the advice people may give you, while caregiving will always be loving, it will also be hurting.

Town & Country 8th Philanthropy Summit – Marlo Thomas × Phil Donahue

The 8th annual Town & Country Philanthropy Summit continued today with a wonderful conversation between Marlo Thomas and Phil Donahue, moderated by Editor in Chief Stellene Volandes. This is the first time that Phil has interviewed Marlo since they first met on the Donahue show decades ago.

Please see below for highlights from the panel as well as a link to view the interview in its entirety:

Marlo on visiting St. Jude following her father’s death:

“After my father died, it was just a terrible shock to us. It was stunning because he hadn’t been sick, so it was very sudden. He was adored by us. We all loved him, and he was our funny, loving perfect daddy so it was very, very hard. We all decided that you know, we’d go to St. Jude and let them know that we were here if they needed us and so I went to St. Jude, a couple of months later. I drove up and there was a sixteen feet statue of St. Jude right at the entrance, and I started to cry because I’ve been there so many times with my dad. I pulled myself together because I didn’t want to cry in front of the parents, they have enough heartache of their own. I went inside and, in the lobby, there was this party going on. All of these little kids running around with party hats, balloons, confetti, ice cream, and cake. I said to the nurse, ‘Well whose birthday, is it?’ She said, ‘Oh it’s not a birthday party, it’s an off-chemo party.’ Well, I’ll tell you, I just gasped, to see these children celebrating one of their turns for the better. All of these moms and dads and grandparents standing around with tears in their eyes because they felt that if this child made it, maybe their beloved child would too. It was really a stunning moment for me. And then, just as I was standing there, this mom came over with a little girl about four years old, all dressed in pink. She had little pink ribbons jauntily tied around her little bald head and the mother said to her, ‘do you know who’s this lady’s daddy is?’ and the little girl shyly answered, ‘yes’ the mother said ‘who?’ She [little girl] proudly said, ‘St. Jude.’ I just fell in love with her. I fell in love with all of those kids in the off-chemo party. I fell in love with this place. And I realized for the first time, just what all of this hope and love and promise and the future of a second chance for children meant to my father. It really helped me to see myself as a part of it.”

Marlo on what she learned from her father: 

“Well, what I learned from dad, really is that he had a lot of sayings, and one of them was there’s two kinds of people in the world: those who stop on an accident to see if they can help or those who just drive by. He was literally the kind that would stop and help. I remember one time, we were driving by down Sunset Blvd. we saw these boys beating up on another little boy. And my father stopped the car and jumped out. He pulled the boys apart and gave them a big talking to. I was sitting in the car, terrified, I was eight years old. He got back in the car. He brought the little boy that’ve been bullied with him. We were going to drop him off at home and as my dad started the car, he said, ‘I hate a bully.’ And I think to him, cancer in children was a bully. A bully that he wanted to defeat. The thing about my dad too is that he really was a citizen of the world, that we all are citizens of the world…He saw himself as part of the neighborhood as a part of a community wherever he was, he was a part of that community. I think that was a great lesson for my sister, my brother, and I.”

Phil Donahue on his first visit to St. Jude and how that impacted him: 

“My first visit to St. Jude, I picked up a little bald-headed kid. I said, ‘What do you want to be when you grow up, big guy?’ This still makes me cry. The kid said, ‘I just don’t want to be sick anymore.’ Well, my god, I grabbed this kid. You know, for a very brief moment, I kind of felt how parents feel when they take a child to St. Jude. How scary it must be and how I didn’t want that child to see my eyes get moist. So, it’s a real learning experience at St. Jude. It changed me forever. I do wish everybody could visit the hospital. It’s a life-changing experience and when you see the parents arrive with a child. You see the real fear on their faces, terror sometimes. Then you see them leaving and they’re better. It’s like a godsent – the change they feel, and that their children feel.”

Marlo on being awarded the Presidential Medal of Freedom and her version of the American Dream: 

“One of the things that happened in my life that was really big a great deal, because of my work with St. Jude, is that I received the Medal of Freedom from President Obama. My husband and I went, and my brother came, and the head of St. Jude came. The interesting thing about it, is when you are growing up, especially as an actress, you dream of getting an Emmy or an Oscar or a Tony, but I don’t think anybody grows up dreaming about the Medal of Freedom. It just comes as a shock when you’re told you will be receiving this at the White House. And I remember I was stunned. Remember we discussed that I wasn’t going to cry? So, I’m not going to cry, but I did because at the moment President Obama was clasping the medal around my neck, I thought of my grandparents. My grandparents were immigrants who came to this country from Lebanon to find a better way of life, to raise their family and their children. And I saw them in my mind’s eye, I could see my grandparents with all their belongings and cloth bags. And here, their granddaughter just two generations later were in the White House receiving the Medal of Freedom from the President of the United States. I mean, that is the American Dream. I’m so proud of the fact that my grandparents made a life in this country.”

Marlo on how celebrity involvement has helped the foundation: 

“That’s a very interesting thing because just as in our generation, we brought in Jennifer Aniston and Robin Williams and all of those wonderful people. My dad did that, that’s how he built the hospital. He used to say this hospital was built with laughter George Burns and the Bob Hope and all of the funny guys—Jerry Lewis and Frank Sinatra, Nat King Cole, Ella Fitzgerald, all of the men and women that were on the night club circuit with my dad helped build St. Jude. In fact, Frank Sinatra did so many benefits that we actually have a whole wing that’s called the Frank Sinatra wing. Their generosity really built the hospital.”

Watch the full summit here.

The T&C Summit continues tomorrow with Stacy-Marie Ishmael speaking to Taraji P. Henson and Jamie Raskin, and Stellene Volandes in conversation with Andreas Dracopoulos. If you are interested in attending register directly here.

Prostate cancer illustration by Heather Skovlund for 360 Magazine

Battle Against Prostate Cancer

New Insights into Hormone’s Action Could Help in Battle Against Prostate Cancer

Discovery Sheds Light on How Cancer Cells Use Androgen

Researchers at UVA Cancer Center have unveiled important new insights into how hormones known as androgens act on our cells – and the discovery could boost efforts to develop better treatments for prostate, ovarian and breast cancers.

The findings shed light on how androgens interact with their receptors inside cells to affect gene activity. This process is important in both healthy cells and certain cancers. Hormone therapy for prostate cancer, for example, aims to reduce the amount of androgen in the body, or to stop it from fueling the cancer cells. However, the approach does not work for some men, and for others it eventually fails. So, scientists are eager to better understand how our cells – and cancer – interact with androgen.

“Our study reveals a new mechanism for how androgen regulates communication within prostate cancer cells,” said Bryce M. Paschal, PhD, of the UVA School of Medicine’s Department of Biochemistry and Molecular Genetics. “Anti-androgen therapies continue to be the cornerstone for prostate cancer therapy. The better we understand how androgens work, the better clinicians will be positioned to understand why it fails, and how even better therapies can be designed.”

Androgen and Cancer

In a new paper in the scientific journal Nature Communications, Paschal and his colleagues describe how a complex signaling system regulates androgen receptor activity. The system, they found, uses a “writer” and a “reader” to modify cellular proteins – sort of like how a computer reads and writes information.

Scientists have appreciated the importance of these modified proteins but understanding just how they influence the androgen receptors has been difficult. One key to the regulation process, found by Paschal and his SOM team, is an enzyme, Parp7, produced by the PARP7 gene. Parp7 is part of a family of enzymes involved in important cellular functions including DNA repair.

Certain cancer drugs already target certain Parp enzymes; these drugs are used to treat prostate, ovarian and breast cancers in patients who have mutations in DNA-repair genes. And while androgens are usually discussed in the context of prostate cancer, androgens may be important in ovarian and breast cancer as well.

Paschal’s new findings offer fresh insights into these Parp drugs and could lead to improved treatments that help patients get the best outcomes. Further, Paschal and his team found lower levels of Parp7 in prostate cancer that has spread to other parts of the body than in the initial tumors. That may suggest that a reduction in Parp7 is associated with the progression of the disease, the researchers say.

With their new androgen insights, Paschal and his colleagues have provided scientists with important new directions to explore in the battle against prostate and other cancers.

“Our next steps will be to use pre-clinical models to determine the role this pathway plays in prostate cancer progression, and whether inhibition of the pathways slows disease,” Paschal said. “We are very excited by what we have learned thus far. Our study emphasizes there is still so much to be learned, and that basic science plays a critical role in defining the molecular context for enzyme and drug action. “

About the Research

The research team consisted of Chun-Song Yang, Kasey Jividen, Teddy Kamata, Natalia Dworak, Luke Oostdyk, Bartlomiej Remlein, Yasin Pourfarjam, In-Kwon Kim, Kang-Ping Du, Tarek Abbas, Nicholas E. Sherman, David Wotton and Paschal.

The work was supported by the National Institutes of Health’s National Cancer Institute, grant CA214872.

To keep up with the latest medical research news from UVA, subscribe to the Making of Medicine blog.

"90s Kids" by Jax artwork by Ted Sullivan via Atlantic Records of Warner Music Group for use by 360 Magazine

JAX – 90s Kids

JAX does it for the “90s Kids”

Multi-talented singer-songwriter premieres nostalgia anthem, available now via Atlantic Records

STREAM “90S KIDS” HERE

Singer-songwriter Jax has premiered her highly anticipated new single “90s Kids” – available now via Atlantic Records. The nostalgia-fueled anthem became an instant fan-favorite after being previewed on TikTok late last year, packed with all the quintessential decade references from Tamagotchi to Britney Spears.

“I’m obviously a 90s kid, and grew up with all these amazing trends that I’m still obsessed with today” said Jax. “One night at 3am I was just thinking of all the times I’d watched ‘Saved By The Bell,’ played Super Smash Bros, danced to Britney Spears and I just put it all in a voice memo. Next thing I knew by sunrise I had this anthem to rep all my fellow 90s babies.”

“90s Kids” follows the release of “Ring Pop,” Jaxs major label-debut which yielded a massive viral response and high-profile appearances on The Ellen DeGeneres Show, Access Hollywood & more. Initially teased on TikTok, “Ring Pop” instantly captivated fans with its honest lyrics that perfectly encapsulate the emotions being felt by so many in today’s predicament. Her warm delivery coasting over dreamy guitar and snappy percussion as she croons to her boyfriend, “Don’t need no diamonds, you’re my rock, and I’m okay with a ring pop.

Raised in New Jersey by way of New York, Jax got her start by performing a wide variety of genres and in bands growing up. At the age of 18, she developed cancer above her vocal cords, which returned following a couple months of remission right as she relocated to Los Angeles in pursuit of her music. Left unable to sing herself, Jax turned to songwriting for others and found industry success behind-the-scenes.

As her ability to perform returned, Jax needed to pivot yet again when the COVID-19 pandemic struck. This time she turned to TikTok, posting a hilarious response to the pop gem “Stacy’s Mom” from “Stacy’s Mom’s Perspective” which exploded with nearly 9 million views in just a few months and “Update from Avril Lavigne & Sk8er Boi 18 years later” which became her most successful parody to date with over 14.5 million views. She continued to go viral a dozen or more times over, eventually amassing over 1.6 million followers on the platform, 200 million total views and 28 million “likes.” With a massive online audience under her belt, Jax began sharing her own original music in late 2020 to an overwhelmingly positive response – ultimately leading to her singing with Atlantic Records for her forthcoming debut full-length.

Science Tech Illustration by Gabrielle Archuleta

Blood Discovery Research x UVA

Blood Discoveries Advance Effort to Grow Organs, Battle Cancer 

New Research Reveals Important Insights Into How Our Bodies Make Blood 

CHARLOTTESVILLE, V.A.– Pioneering research into how our bodies manufacture the cells that make blood has moved us closer to regrowing tissues and organs. These findings also may let doctors grow the cells for transplantation into people to battle cancer, blood disorders and autoimmune diseases.

Researcher Karen K. Hirschi, PhD, of the Department of Cell Biology and Cardiovascular Research Center at the University of Virginia School of Medicine, has developed a simple and efficient way to generate “hemogenic endothelial cells.” These cells are the first step in the production line of blood cells, and Hirschi’s new findings provide a blueprint for creating them outside of the body.

“By studying how hemogenic endothelial cells develop normally, we gain the insight needed to generate them in the lab,” Hirschi said. “Now that we have established a method to produce human hemogenic endothelial cells outside of the body, we will continue to improve their production and function as we learn more about the mechanisms that promote their normal development.”

Building Blood-Making Factories

Hirschi’s latest work, published in a pair of scientific papers, offers important insights into how hemogenic endothelial cells form, and how they ultimately give rise to the cells that directly manufacture blood.

Writing in the prestigious journal, Science, she and her team reveal a key trigger that causes the endothelial cells to “transdifferentiate,” or turn into blood-making factories, during embryonic development. These blood-making (i.e. hemogenic) endothelial cells generate hematopoietic stem and progenitor cells (HSPCs) that have long been used for the treatment of cancer and other diseases. Typically, they are taken from sources such as an individual’s bone marrow, but doctors would like to be able to manufacture them quickly and easily for patients on demand. “Generating human hemogenic endothelial cells in the lab from each patient that needs HSPC is the first step toward patient therapies for blood disorders,” Hirschi said.

In a paper published nearly simultaneously in Cell Reports, Hirschi unveils a blueprint for creating the hemogenic endothelial cells, the source of HSPCs, outside of the body. The secret is a substance called retinoic acid. You may have heard of retinoic acid in association with beauty products, but in this case its responsibilities include triggering genes to cause “hematopoietic transition”–to put more vascular endothelial cells in the business of making blood by producing HSPCs.

The new insights provided by the work “will improve our ability to apply developmental insights to the generation of distinct endothelial cell subtypes for tissue engineering and regenerative medicine,” the researchers write in their new paper. “In addition, our system could likely be developed further to optimize the generation of transplantable HSPCs from human hemogenic endothelial cells for clinical therapies.”

The approach offers several advances over existing means, including being quicker and less expensive, the researchers note.

“We hope our continued efforts will move us closer to treating both vascular and blood disorders,” Hirschi said. “These studies highlight the importance of basic cell and developmental biology research as a foundation for devising strategies for patient-specific clinical therapies.”

Hirschi was recruited from Yale in 2019 to join the faculty in the Department of Cell Biology, which has long been interested in addressing how embryos develop and applying this basic knowledge to the repair and regeneration of damaged tissues and organs.

Findings Published

The Science paper was authored by Dionna M. Kasper, Jared Hintzen, Yinyu Wu, Joey J. Ghersi, Hanna K. Mandl, Kevin E. Salinas, William Armero, Zhiheng He, Ying Sheng, Yixuan Xie, Daniel W. Heindel, Eon Joo Park, William C. Sessa, Lara K. Mahal, Carlito Lebrilla, Hirschi and Stefania Nicoli. The work was supported by the National Institutes of Health (grants F32HL132475, U54DK106857, 1K99HL141687, R01HL130246, R56DK118728, R01HL146056. R01HL128064, R01DK118728 and R01GM049077) and the American Heart Association (grants 19PRE34380749 and19TPA34890046).

The research team responsible for the Cell Reports paper consisted of Jingyao Qiu, Sofia Nordling, Hema H. Vasavada, Eugene C. Butcher and Hirschi. That work was supported by NIH grants HL128064, U2EB017103, R01-AI130471 and R01-CA228019; CT Innovations grant 15-RMB-YALE-04; Department of Veterans Affairs Merit Review award I01BX002919; the Swedish Society for Medical Research; and a Stanford Dean’s Fellowship.

To keep up with the latest medical research news from UVA, subscribe to the Making of Medicine blog at http://makingofmedicine.virginia.edu.

Summer Watson inside 360 MAGAZINE

Premiere: Summer Watson Inspires People To Take Their Masks Off And Show Their Core On New Single “Unveiled” 

The wonderful Classical crossover icon, singer-songwriter Summer Watson, is releasing a much anticipated new single, “Unveiled,” following-up on her previously released song “Break The Silence.” Both singles are off her upcoming album, also titled Unveiled. Summer Watson has graduated from the Royal College of Music, and throughout her education, she has received numerous individual awards and grants. Blending her classical textures with pop sonic constructions, Summer is the first-ever classical artist to sign a £1mln deal with Sony Music, which comes as no extraordinary fact once we listen to her hypnotic and incredibly beautiful voice. This time, Summer Watson is releasing her own music, after singing other artists’ music for years. What radically changed her approach in life is a series of difficulties to face, among which being diagnosed with stage 4 breast cancer. It is noteworthy to mention that she has overcome cancer with natural treatments only, as she refused to undergo chemotherapy. Her warrior spirit and skills to adapt to new situations have helped her become a stronger version of herschel;f than she ever was before. 

Both “Break The Silence” and “Unveiled” are aligned in their purpose and mission; to heal and be true to oneself. She is a lyrical healer, and uses music as a powerful tool of expression to help others overcome and understand what she herself has painfully learned along the way. The LA-based classical crossover star is rapidly and exponentially expanding her fan base this year, with her wisdom, beauty, and charisma simply being mind blowing, and after listening to the first two parts of her upcoming album, we are highly anticipating its release. 

Listen HERE.

Kaelen Felix illustrates article for 360 MAGAZINE

Finding New Light

by Sonya Keshwani, two year breast cancer survivor & founder of StyleEsteem Wardrobe

There are many things no one tells you about getting diagnosed with breast cancer at 29 years old. How you will meet physical limits you didn’t know existed, and then keep pushing beyond them. How your entire identity – past, present and future – will be viewed through the lens of your diagnosis. And how the diagnosis and healing process are much more challenging and tough than pinkwashed TV commercials would have you believe. 

Through all these instances, every cancer patient experiences moments when they have to make a decision to either see themselves as a continuous human being experiencing cancer and healing, or as a new person who is living a second chance life. I saw a third option for myself. I decided that the person who was going to be a “survivor” deserved to wear her challenges as beautiful accomplishments, while also appreciating the fullness of her new life. 

Since a young age, fashion had been a medium for expressing my joy and vibrancy. So when I lost my hair to chemo, I channeled that same approach into the creation of fashionable turbans. Through the lens of beautiful fabrics and patterns, I learned that challenging situations are wrought with beauty and sparkle. I started the shift from seeing my bald head as a symbol of cancer, to seeing myself – my true character and strength – as beyond skin deep.  I went from creating new styles between chemo sessions, to launching a company that empowers women through cancer and hair loss, called StyleEsteem Wardrobe. This company and the mission to help others became my “why” on the path to healing.

One of the greatest blessings of my “why” is how it has enabled me to connect with other profound individuals and organizations on a similar mission – to improve and empower the quality of life for cancer patients. Earlier this year, my “why” brought me to A Silver Lining Foundation gala in Chicago, where I met Twist Out Cancer Advisory Board Member Gudrun Wu Snyder. We instantly connected as she told me about Twist Out Cancer, a place where cancer patients’ stories are turned into inspirational works of art. Their mission and the story of their founder, Jenna Benn Shersher, spoke to me like a glittering beacon of hope, similar to the one that inspired me during the creation of StyleEsteem. Right away, I knew I wanted to get involved, so Gudrun encouraged me to apply to the Brushes with Cancer program. 

When I was selected as an inspiration for the Brushes with Cancer 2020 Chicago cohort, it was an emotional experience for me. Like we are told when we are young “you can be anything you want to be when you grow up”, I similarly told myself this as a cancer patient. That I could be anything through cancer – inspirational, fashionable, fierce and graceful. Two years into my survivorship, what I had told myself in my heart was being amplified by others in my community, and this alone was such a powerful experience for me. 

My pairing with my artist, Sujata Gazder, a talented, intuitive and bold fashion designer, couldn’t have been more perfect. She saw beneath the surface of my diagnosis, into a story of family unity, broken stereotypes, and audacious hope. She saw my diagnosis as a catalyst for taking back control of my joy and my purpose in life. And we both agreed that hair loss was not loss entirely, it was the adornment of something new and beautiful in my life. 

Due to the pandemic, as well as Sujata being based out of Chicago and me being based out of New York, creating the final masterpiece had unique requirements from each of us. Phone catch ups, Zoom fittings, and photo sneak peeks of her work in progress.  The dress beautifully and perfectly honored each element of my survivorship, from my hair journey and attitude, to my family and spiritual roots. I was amazed at how Sujata could create something I so deeply connected with after knowing me for such a short period of time. 

Outside of my experience with Sujata, being part of this cohort has bonded me with countless other individuals who found their own path to beauty through the darkness of diagnosis. I am proud to stand among them as a survivor and a supporter. And I am so grateful for this space where our stories are transformed into inspiring works of art and unforgettable experiences.

Today I look forward to our virtual gala where we will celebrate each other’s stories, and to seeing my gown in person for the first time when I meet Sujata. This process has taught me that diagnosis is like a crystal. Whoever is holding your crystal in their hands can see new beauty, color and light in your story. And when you exercise vulnerability and trust to let that happen, you can find new meaning and purpose in your own path.

CBD vape cartridge illustration for 360 MAGAZINE

Who Can Use CBD Vape Cartridges


Vaping is a method of taking CBD that became popular in the last years, and there are many reasons for this. The leading one is the effectiveness of this compound and its health benefits. Then, there is the ease of use, convenience, and swift action of CBD after inhaling.

The safety of cannabidiol use is also one of the main reasons why this substance is a buzz. Vaping, as explained on Cheef Botanicals, is a way to administer CBD that has the least side effects. If you use vape gear and cartridge according to the instructions, the risk of abuse is minimal.

Whether this natural remedy is used as a supplement or adjunct to conventional therapy, it is suitable for both healthy and sick people. Still, in some people, vaping will have an excellent effect. This method of CBD ingestion is especially recommended to them.

People Suffer from Anxiety

Depression and anxiety are common conditions that can have devastating effects on health and well-being. These mental issues always lead to many difficulties in all areas of life. Sufferers try to keep these conditions under control using medication.
Still, no matter how effective, conventional drugs often have many side effects. Even worse, they can be addictive. Natural remedies like CBD have minimal side effects and are safe for use whenever you feel upset or depressed.

CBD is proving to be an excellent choice for relieving all the symptoms of anxiety. The healing properties of this compound reflect in its positive effect on receptors in the brain. CBD ingested through vaporizers can affect how these receptors respond to serotonin. That way, it reduces nervousness, stress, and depression.

Everyone with Sleep Issues

Sleep issues don’t always manifest as a disease, but these are not normal condition as well. In some people, poor sleep can be an acute problem. It can occur for various reasons – night work, rest, time zone changes, etc. Also, insomnia can be directly related to stress and anxiety. People who feel anxious have trouble falling asleep and sleeping continuously. That is why it’s necessary to act first on the cause of insomnia and then on this condition.

As described in the previous paragraph, CBD’s soothing effect will help anxious people improve their mood and get rid of anxiety. As for sleep, that means it will be easier to fall asleep and have more extended periods of sleep without interruption.
Why people need a quality night’s rest, read on the following source:
https://www.popsci.com/why-we-need-sleep/ 

People with Arthritis

Arthritis is the leading condition among many others that occur as a result of inflammation. There is still no cure for this disease, and those currently in use can have harmful effects on inner organs. That is why more and more patients turn to natural remedies that can be used along with prescribed therapy. They don’t damage the kidneys, pancreas, and heart.

Some receptors in the endocannabinoid system are responsible for the proper functioning of the immune system. They also keep the inflammations under control. CBD affects these receptors, which means it directly treats the cause of arthritis. It also reaches the painful place where it ‘fixes’ the damage.

Cancer Patients

Chemotherapy is a cancer treatment that gives outstanding results but often has some side effects. Read more about them on this web source. They are not risky, but they reduce the quality of life of a cancer patient.
 Sometimes it can last for years after treatment is completed. These are most often neuropathic pain, chills, appetite disorders, nausea, fainting, and many others. CBD can help people struggle with these adverse effects of chemo. 

Thanks to its anti-inflammatory and analgesic features, this compound acts as pain relief. Thus cancer patients who vape CBD don’t feel neuropathic pain. They are in a better mood, have a healthier appetite, and so on. All these mean these people can return to daily activities soon after chemo.

Inhaling CBD is a safe way to provide your body with the dose of cannabidiol needed to treat or prevent disease. This substance affects many processes in the body, which means it can help treat and fix the damages resulted from diseases.