Posts tagged with "anti-aging"

Harnessing the Nine Hallmarks of Aging: to live your healthiest life by Greg Macpherson for use by 360 Magazine

Reversing the Aging Process At A Cellular Level

By: Greg Macpherson, pharmacist, author, “Harnessing the Nine Hallmarks of Aging

You might think that the occasional gray hair, fine line and wrinkle starting to stare back at you in the mirror is a sign that time is starting to have its impact felt, but these visible changes as we age are just a symptom of what has been going on at a cellular level inside your body for decades. We all know that you can’t change time, but recent advances in our understanding of aging at a cellular level mean that in the not too distant future we will be able to change the impact that time has on our cells.

And it’s about time. Right now, despite the decades and billions of dollars that have gone and continue to go into attempting to understand and solve the diseases associated with advancing age like Alzheimer’s disease, Parkinson’s disease and cardiovascular disease, we have not made the progress we should.

Researchers are now starting to ask the question – what if we change track and seek to understand the aging process? By slowing aging, we not only spend decades longer in good health, but we push the diseases associated with old age down the road–possibly avoiding them all together.

 Why We Decline with Age

With better questions come better answers, progress, and breakthroughs. Nearly a decade ago, in the absence of a single theory regarding aging, scientists reached a consensus on nine key areas of our cells that decline in function as we age. These key areas are called the nine hallmarks of aging, and they all have something in common. If you make them worse, you age faster. If you make them better, you slow the aging process down.

Identifying the hallmarks of aging has given researchers cellular targets to focus on, and has unleashed an incredible amount of human capital focused on solving, or at least reducing, the ravages of aging on our bodies. Researchers armed with tens of billions of dollars in research grants and private equity are now racing to find the answers. And the prize is huge–resolving the aging process, deferring the diseases of older age and extending the time we spend in middle age in good health by decades will transform humanity and will both disrupt and create a trillion dollar industry overnight.

Progress is being made at an accelerating rate, and there are now therapies that have  been proven in mice models that are now making their way into clinical studies. Rapamycin, a pharmaceutical that is typically used for organ transplant recipients, because of its ability to help the body avoid rejecting the organ, is now understood to extend life in mice by up to 60%. Senolytics, molecules that help the body identify and remove senescent cells that increasingly accumulate as we age and literally poison the healthy cells that surround them, have extended life in mice by up to 30%. Metformin, a drug used to treat Type 2 diabetes has been identified to significantly reduce cancer rates and extend life.

And these are just a few of the compounds that have been identified that shift the effect of time on our bodies. These and more molecules being developed right now, plus strategies for healthy aging that have been identified from the blue zones around the world where people live to 100 and beyond at a much higher rate than the rest of us, are amongst the many healthy aging strategies that I featured in my book, “Harnessing the Nine Hallmarks of Aging, to Live Your Healthiest Life.”

As a pharmacist with 30 years of experience, I have spent the last decade working in the biotechnology arena associated with anti-aging, translating the complex world of anti-aging science to make it available for the rest of us. By understanding the nine hallmarks of aging­–adopting simple strategies from the blue zones, and sharing the breakthrough molecules that have not been available to humans in previous generations– I’ve put together a step-by-step, healthy aging strategy. We can all adopt  this strategy and, in the process, significantly alter our aging trajectory and making healthy aging much more of a certainty.

Why DNA Matters

One example of a hallmark of aging is “genomic instability,” which is another way of saying that the negative changes to our DNA in our cells that happen as we age. Your DNA is your cellular instruction set and defines what it means to be a human versus every other living species on our planet. Your DNA is responsible for the difference between a skin cell and a heart cell, a neuron and an insulin producing cell.

Your DNA are molecules that sit at the center of almost every single cell in your body, helping it function, live and thrive. Your DNA does this in an incredibly hostile environment as it deals with the external stress of pollution, mutagenic foods and chemicals, UV light and X-rays, and the internal insults of oxidative stress. Due to these factors your DNA is damaged between 50,000 and 100,000 times per day, per cell.

Because of the importance of having a healthy instruction set, your cells spend a huge amount of resource on the repair and maintenance of your DNA and as we age, and this process starts to decline, which has significant effect on the health of your cells. Take a quick look at the back of your hand compared to the skin on the inside of your wrist to get a sense of the difference between cells exposed to UV damage that hits your DNA.

DNA damage is happening right now in every cell in your body, and over time it affects the ability of your cells to function effectively. Starting as early as your 30s, by supporting DNA repair and maintenance through making lifestyle changes and by taking molecules, like hobamine, NMN and apigenin, as outlined in my book, it can help your body keep your DNA and the other hallmarks of aging in good shape. By following the roadmap of this breakthrough strategy in a healthy aging, you will age better than previous generations have ever been able to achieve.

Biography

Greg Macpherson is a pharmacist, entrepreneur and author of, “Harnessing the Nine Hallmarks of Aging: To Live Your Healthiest Life.” For more than a decade, he has been working in the biotechnology sector, specifically focusing on the aging process at the cellular level. This work led him to discover ways to harness the nine identified, scientific hallmarks of aging, which is the premise of his book that addresses the natural aging process, how to age more favorably and simple strategies to slow the aging process and build a functional longevity plan. Beyond theory and concept, Macpherson has used his entrepreneurial spirit to further develop solutions to this new paradigm of aging, described in his book, by launching SRW Laboratories, a science and research based company that curates the latest biotechnology research to formulate natural products designed to help slow the onset of aging and disease, and develop evidence based solutions for those who are experiencing age-related health concerns. SRW, which stands for Science, Research and Wellness, is Macpherson’s natural world laboratory that will develop the preventative formulas from nature required to slow down the aging process based on the nine hallmarks of aging, which include mitochondrial dysfunction, telomere attrition and cellular senescence, to name a few. With aging being the single biggest risk factor for developing disease, Macpherson’s mission to slow the aging process at a cellular level could help millions of people delay the onset of diseases associated with advanced aging like Alzheimer’s and heart disease.
greg macpherson headshot for use by 360 Magazine

Cannabis illustration by Rita Azar for 360 Magazine

Holistic CBD Beauty Therapy

When OLIVEDA founder, Thomas Lommel, discovered the active ingredient cannabidiol/CBD, he researched the great synergy effects that arise in connection with the legendary cell elixir from the olive leaf and developed a new beauty line for inside and outside:

LA DOPE is a holistic, highly active cosmetic based on the power of the two oldest cultivated plants in the world. It combines the legendary active ingredient cannabidiol from the hemp plant with the highly active antioxidants oleuropein and hydroxytyrosol from the olive leaf to create powerful beauty grenades.

LA DOPE­ provides protection and care with 100 percent pure effectiveness because all products contain the precious cell elixir from the olive leaf, instead of water. Due to the globally unique composition of the emulsions, LA DOPE works with the intelligence of nature, which intuitively recognizes the individual texture of the skin and its current needs. LA DOPE actively regenerates and balances skin’s texture on this basis.

True to the OLIVEDA tradition, LA DOPE is also holistically oriented, starting with products for internal use, and then devoting itself to the skin with various serums, oils and creams.

The synergy effect from the transforming energy of cannabidiol with the extraordinarily protective and regenerative effects of the cell elixir from the olive leaf makes LA DOPE the perfect CBD, holistic beauty therapy. For beauty that comes from within and radiates outwards. Dope your wrinkles from within with Oliveda and LA DOPE.

 

CBD, Vaughn Lowery, 360 MAGAZINE

Why You Should Add CBD To Your Skincare

Cannabidiol, also known as CBD, gets a lot of attention for treating chronic conditions such as pain, anxiety, insomnia, even seizures. And while it does offer health benefits, you shouldn’t overlook CBD’s potential for beauty benefits, too.

CBD in skincare can offer a solution for inflammatory skin conditions, support for sensitive skin, and a way to fight the signs of aging. It’s a natural, plant based product that can help your skin.

What is CBD?

CBD is a cannabinoid derived from the cannabis plant. Cannabis is known for another popular cannabinoid, THC, but unlike THC, CBD won’t get you high.

It works as an anti inflammatory and antibacterial tool, and can offer a host of benefits for your skin when used topically:

  • Rejuvenation
  • Brightening
  • Smoothing wrinkles
  • Relief for dry skin
  • Soothing sunburned skin

CBD is available in a variety of skincare products. You may see CBD in products such as:

  • Moisturizers
  • Lotions
  • Body creams
  • Facial serums
  • Masks
  • Face creams
  • Cleansers
  • Exfoliants
  • Soaps
  • Body wash
  • Eye serums
  • Eye creams

How Does CBD Help Skin?

Offering anti-inflammatory properties, CBD can calm your skin and can treat skin imbalances. That means it may be a good choice for conditions such as acne, eczema, dry skin, psoriasis, or sun damage.

CBD oil is rich in antioxidants, and has vitamins B, C, and E. It also offers healing fats omega 3 and omega 6. Some skincare products combine CBD with other skin soothing ingredients such as shea butter and aloe vera.

What to Know About Using CBD For Skincare

CBD products are legal at the federal level. However, some states have their own restrictions on CBD, so it’s a good idea to check before you start using CBD.

Look for products with hemp oil. Hemp oil has CBD in it, coming from the buds and flowers of the hemp plant.

Be careful to keep in mind the CBD is somewhat of a beauty buzzword, and while you might find it on the label of many products, that doesn’t necessarily mean it offers the full potential of CBD. You’ll want to know how much CBD a product has, and the quality of the CBD. The product should be independently tested for purity.

Find out how much CBD the product has. Look for a third party testing certificate that indicates the amount of CBD and other compounds in the oil. Ideally, you should look for CBD skincare products with 25mg to 250 mg of CBD per ounce.

A little goes a long way. You don’t have to replace your entire skincare routine all at once with CBD. It’s enough to pick a few key items here and there. For example, it could be helpful to replace your night serum with a CBD version, or swap out your body wash.

If you’re curious about using CBD skincare products, consider what might be the most helpful for you. Look for products that can support healthy skin both with and without CBD, and take care to consider product quality, purity, and potency.

Amelia Noble is a researcher with the CBD Awareness Project. When she’s not working, you can find her playing board games. 

ANDAZ MAYAKOBA RESORT RIVIERA MAYA

ANAUM WELLNESS & SPA AT ANDAZ MAYAKOBA RESORT RIVIERA MAYA LAUNCHES NEW MENU

~ Refreshing New Spa Menu Highlights Local Ingredients, Beauty Partners and Mayan-Inspired Treatments in Lush Natural Setting ~

 

360 Magazine, ANDAZ MAYAKOBA RESORT RIVIERA MAYA     360 Magazine, ANDAZ MAYAKOBA RESORT RIVIERA MAYA

 

Naum Wellness & Spa, the 10,000-square foot verdant wellness hideaway at Andaz Mayakoba Resort Riviera Maya, has just launched a new spa menu. The new menu, which incorporates many local and natural ingredients, brings in traditional Mayan rituals and offers a variety of spa services promoting health, beauty and inner harmony. The spa’s namesake, Naum, is the Mayan God of consciousness and mind. The Mayan-influenced spa, whose décor follows the same theme as the menu, is simply designed to blend into its lush jungle surroundings, immersing guests into the culture and nature of the region. The six open and airy treatment suites have oversized windows with beautiful decks and striking green views that bring guests a sense of peaceful relaxation.

The new spa menu, which has been carefully curated by Spa Manager Daniel Escalante, is inspired by native Mayan traditions known as “rituals”, which are reflective of the mind, body and spirit. The new treatment Rituals on the menu include the Ritual Sac Ki, which frees the body of harmful toxins and reveals fresher and brighter skin with a dry exfoliation using “Sac Ki”, the Mayan word for white henequen considered the green gold for the Mayan culture. This is followed by an invigorating massage with the anti-inflammatory power of the sacred copal oil. The second Ritual is the Ritual de Ixi’im y Chia, which offers the antioxidant power of the exotic Blue Corn and the purifying power of “Chia”, the Mayan word for “Strength”. The treatment also includes a nourishing massage with shea butter enriched with the regenerative benefits of calendula extract. Couples can reconnect with each other and renew their love through one of the Lovers Retreat rituals including the Eternal Romance Ritual which combines Swedish massage and hot stones with the exquisite aphrodisiac synergy of clove essential oil and wild roses. Rituals range from 90 to 120 minutes and are priced between $349 for a single treatment to $539 for the couple’s treatments.

The Naum Rituals were created to pay homage to oneself and the Mayan Gods, and to find harmony based on the guest’s selected area of wellness intention – whether that be Clarity (Tsoolik), Rest (He’lel), Strength (Muuk’) or Connection (Molcintah). Each Ritual is a three-part experience, alluding to the balancing nature of the number three with a beginning, middle and end. The Rituals begins with a Mayan Time of Reflection, followed by the treatment experience itself, and concludes with a Mayan Celebration to help guests balance and reconnect with themselves and the universe.

Apart from the traditional Rituals, spa guests can also choose from a selection of facials, massages and body treatments, many of which feature local and natural ingredients. Valuing the importance of the science of beauty care, Andaz Mayakoba created specific treatments in partnership with innovative beauty brands such as Naturopathica and Barbor, renowned for their high-quality formulas that contain natural plant extracts mixed with technology to combat a variety of skin problems.  Highlights from the new menu include the following:

 

Naum Signature Treatment, 90 minutes, $316

This unique four-hand sensory treatment combines Volcanic Stones, Swedish Rhythmic techniques and a custom synergy of essential oils to stimulate the vital energy of the body, and brings all muscles and senses to maximum relaxation reaching the connection between mind, body and spirit.

 

Mayan Stone Massage, 60/90 minutes, $167/$237

This Mayan-influenced massage induces the flow of vital energy through the stimulation of each of the body’s centers, harmonizing mind, body and spirit, in addition to improving the circulatory system and releasing toxins from the skin.

Vitamin C Facial by Barbor, 60 minutes, $192

The Vitamin C Facial by Barbor is a true cosmetic jewel that contains a fresh texture and revitalizing citrus aroma for all skin types, including the most damaged. With an active concentrate of 20% Vitamin C, the treatment increases the production of collagen and the luminosity of the skin for a smoother complexion and firm and bright skin tone, protecting the skin from the sun.

Gentleman’s Facial by Barbor, 60 minutes, $192

The Gentleman’s Facial is a barber style facial designed for the demanding male skin, which is subject to stress. Taurec, the powerful exclusive active ingredient of the series BARBOR MEN, soothes the skin and enhances its energy and vitality.

Anti-Aging Facial by Naturopathica, 90 minutes, $264

In partnership with Naturopathica, the anti-aging facial is a reparative, regenerating and corrective treatment that combats the signs of aging. Active ingredients Argan Plant Stem Cells, Matrixyl synthe’6 and a Tri-Retional blend work together to help reduce fine lines and wrinkles while improving skin tone and firmness.

 

Xoco – Tequila Body Wrap, 60 minutes, $187

This locally inspired treatment revitalizes the skin and combats stress with powerful Mexican antioxidants. Chocolate and tequila, in addition to being delicious delicacies, have the ability to preserve beauty and youth while relaxing the mind and senses on a path to emotional well-being.

Jade Oro y Plata Body Wrap, 60 minutes, $187

This natural body treatment embodies mineral and dazzling wisdom with this ancestral elixir of jade, gold and silver, stimulating cell regeneration, blood circulation and bringing luminosity to the skin.

The spa offers an array of additional services ranging from hand and feet rituals to wellness experiences including yoga, meditation and personal training. Access to Naum Spa’s Hydrotherapy services are complimentary with the purchase of any spa ritual.

“After seeing the success of our Naum Wellness & Spa in our first year of opening, we are excited to debut a completely refreshed menu for our valued guests,” said Spa Manager Daniel Escalante. “We have partnered with innovative beauty brands that share our values of sustainability and holistic well-being and have introduced new treatments and rituals that incorporate indigenous methods and local ingredients that are native to Mexico. From the moment they step in the spa, guests will have a completely immersive and authentic experience into the region’s nature and culture.”

For more information, visit: http://mayakoba.andaz.hyatt.com/en/hotel/home.html.

 

About Andaz Mayakoba Resort Rivera Maya
The newest addition to idyllic Mayakoba, Andaz Mayakoba Resort in Rivera Maya, Mexico invites guests to a hidden paradise – a place where style meets nature in an innovative hospitality experience. The resort’s breathtaking design reflects the native Mayan culture and features 214 guestrooms, including 41 luxury suites. Stimulating upscale experiences entertain guests, whether immersing in a lushly preserved mangrove environment, sunbathing in one of two outdoor pools, relaxing in the 10,000-square-foot Naum Wellness and Spa, experiencing the state-of-the-art Kimbo Kid’s Club, or unwinding on the pristine white sanded Caribbean beach. For meetings and events, the property offers 14,000 square-feet of versatile indoor and outdoor meeting space. Additionally, four unique restaurants and bars offer the distinguished culinary experiences for which Andaz® hotels are known for, and all with stunning views of the pools, lagoon, and ocean. Andaz Mayakoba Resort brings to life locally inspired and indigenous experiences and authentic Mexican hospitality. For more information, please visit andazmayakoba.com and follow at facebook.com/andazmayakoba, twitter.com/andazmayakoba, and instagram.com/andazmayaoba.mx.

About Andaz
Global in scale while local in perspective, Andaz hotels weave the sights, sounds and tastes of their surroundings into each property for an experience that truly immerses guests in the eclectic culture of each local destination. Through personalized, unscripted service, Andaz creates a barrier-free environment where guests are encouraged to explore their personal sense of style and become inspired by the spirit of the culture around them. Sixteen Andaz hotels are currently open: Andaz 5th Avenue and Andaz Wall Street in New York, Andaz San Diego, Andaz West Hollywood, Andaz Napa, Andaz Scottsdale Resort and Spa, Andaz Savannah, Andaz Maui at Wailea, Andaz Ottawa Byward Market, Andaz Mayakoba Resort Riviera Maya, Andaz Peninsula Papagayo in Costa Rica, Andaz London Liverpool Street, Andaz Amsterdam Prinsengracht, Andaz Delhi, Andaz Xintiandi in Shanghai, and Andaz Tokyo Toranomon Hills. For more information, please visit andaz.com. Follow @Andaz on FacebookTwitter and Instagram, and tag photos with #WhenInAndaz.

PUR ATTITUDE x CELL RENEWAL NIGHT CRÈME 

PUR ATTITUDE™ LAUNCHES ADVANCED CELL RENEWAL NIGHT CRÈME 

 

An Overnight Skincare Product with Natural Polymer Time-Released Technology, Bio-Advanced Peptides and Fermented Oil

 

PUR attitude™  released Advanced Cell Renewal Night Crème, a high-performance anti-aging cream that delivers key ingredients into the skin overnight via a natural polymer time-released technology. The cream also leverages bio-advanced peptides that oxygenate the skin and promote cell renewal, and fermented oil to improve youthful suppleness of the skin.

 

“The beauty of the PUR attitude brand is that we can deliver such advanced technology using safe ingredients,” said Jerry Rayman, President of PUR attitude. “The science behind anti-aging skincare is developing at a rapid rate. The products have better performance than ever before. PUR attitude is delighted to deliver yet another high-performing product to the marketplace.”

 

Advanced Cell Renewal Night Crème is enhanced with the power of natural Hyaluronix™ technology, which delivers up to one thousand times its weight in water, binding moisture deeply into the skin. This night cream uses a complex of three different molecular weights of Hyaluronic Acid—combined with glucosamine and ceramides—to create a delivery system that encapsulates and time-releases key ingredients deep within the lower layers of the skin. The cream also delivers a bio-advanced peptide technology along with Acetyle Hexapeptide-3, which has been proven to help reduce the signs of aging.

 

While the health benefits of eating fermented, probiotic foods are widely accepted in the food industry at this time, their use in skin care is relatively new. Fermenting natural oils restructures complex molecules, transforming them into tiny “superfoods” for the skin, providing faster absorption that results in healthier, younger-looking skin. Advanced Cell Renewal Night Crème uses a fermented olive oil for superior performance.

 

Each product in the PUR attitude line is dermatologist tested and approved, backed by independent clinical studies, and follows the brand’s standards for “Safe Beauty,” avoiding harsh chemicals, parabens, PEG’s, glycols, sulfates, petro-chemicals, synthetic fragrances and artificial dyes.

 

Advanced Cell Renewal Night Crème is available in 1 fl oz at a retail price of$59. (This is approximately a six-week supply, when used once daily). For more information, visit www.PURattitude.com.

 

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About PUR attitude

Based in Boca Raton, Florida, PUR attitude products contain only safe beauty ingredients and are not diluted with water. More than 1,300 chemicals have been banned from the company’s lab, which adheres to strict EU standards. All formulations for the brand were developed by David Pollock, a beauty innovation chemist with more than 20 years of experience formulating products for some of the most recognized names in the industry.